Heba M Zamil, Alshimaa M Elmalawany, Yasser BM Ali, Ahmed A. El-Shaarawy, Roba M Talaat

Background: Circulating microRNAs (miRNAs) have been reported as a promising epigenetic biomarker. miRNAs have significant diagnostic potential for hepatocellular carcinoma (HCC). In this study, expression of miR-17-92 in Hepatitis (C)-related Liver Cirrhosis and HCC was evaluated. miR-17-92 expression was assessed using quantitative real-time Polymerase chain reaction (RT-PCR) in 145plasma samples [45 healthy controls, 25 HCC patients, and 75 cirrhotic patients with various Child-Pugh stages]. The relation between miR-17-92 and paternally expressed 10 (PEG10) and Phosphatase and tensin homolog (PTEN) proteins were investigated. Results: Our study found a significant reduction in miR-17-92 expression (P<0.001) in HCV-infected patients [either cirrhotic or HCC patients] when compared with the healthy control group. miR-17-92 expression levels with a cutoff value of 1.175-fold change had a 64% sensitivity and 34.9% specificity. With a cutoff value of 8.5 ng/ ml, alpha-fetoprotein (AFP) had a high sensitivity (87.5%) and specificity (100%) in the detection of HCC. BothPEG10 (P<0.001) and PTEN (P<0.01) were significantly decreased in HCC patients as compared with the healthy controls. The detection of miR-17-92, PEG10, and PTEN is valuable in elucidating the complex regulatory mechanisms governing HCC tumorigenesis. Conclusions: The combined detection of these factors may have clinical importance in prognostic, diagnosis, judgment, and therapeutic options for primary HCC.A future prospective large-scale study is recommended to support our findings and prove the mechanistic connections between miR-17-92 and PEG10/PTEN levels and HCV disease manifestations.

Ndoumbe Mateke Max, Nyobe Yome Jean Maurice

In this work, a direct torque control (DTC) method for four-wheel drive electric vehicles (EVs) is applied. Each wheel has an induction motor that provides its motion. Firstly, the DTC control method associated with the model-referenced adaptive system (MRAS) is used for speed control, and the management of magnetic quantities is provided by the variable master-slave control (VMSC) to the topology of the vehicle under investigation. In order to increase the technical performance of the studied system, a DTC method has been combined with a fuzzy logic approach. For this scenario, the control and management mechanisms of the dynamic and magnetic parameters are unchanged except for those with a speed that can be regulated via the PI. An electronic differential (ED) is used to control speeds during specific phases such as turning, climbing, and descending. The proposed control method allows highlighting the speed, accuracy, stability, and metric robustness during specific stress tests imposed on the wheel motor. The results obtained in MATLAB/Simulink software allowed us to compare the technical performances obtained against other control methods. The DTFC control method responds favorably to electric vehicle traction chain systems by the nature of the comfort and safety provided

Omar Ahmad Alqahtani

Cascade control is one of the control systems that improve the performance of industrial processes in the event of a disturbance. Which enhances access to high quality products. This paper deals with cascade control system, its field of use, how to choose the appropriate control effects for the secondary controller, methods for tuning these controllers, and how to protect the control system from reset windup.

Wahdan M. A. Elkwatehy, Rabab I. Salama

Background: Hypersensitivity of dentin is a common dental problem with a varied effectiveness of the different available treatment modalities. Aim of the work: Clinical evaluation of the effectiveness of different fluoride containing varnishes in treating dentinal hypersensitivity of exposed dentin. Materials and methods: A clinical trial was conducted on 108 teeth prepared for fixed prosthodontics divided into three equal groups according to the varnish used. Clinpro XT, Sliver diamine fluoride and Bifluoride -10 varnishes were used to protect the dentin after teeth preparation. Thermal and evaporated stimulus were used, and dentin hypersensitivity was evaluated using Visual Analogues Scale. Intraclass coefficient was performed to ensure the reliability between the data of the testing methods. One-way and repeated ANOVA were used for comparison among the different tested materials at different follow up intervals measurements. Results: The three groups showed significantly decrease on dentin hypersensitivity after immediate application and after one week (p < 0.000). Varnish XT and Silver diamine fluoride showed lower significant mean values than bifluoride varnish with no significant difference between them. Conclusion: All tested varnishes were significantly effective for reducing dentin hypersensitivity. Clinpro XT and Sliver diamine fluoride have nearly similar effect which was significantly better than Bifluoride -10 varnish.

Wijanarka

This paper aims to describe the water-based architecture in Kalimantan and describe the study of the development of Ark’a Modulam Foundation. The method used is description. the conclusions resulting from this paper are: 1). Historically, Indonesia has always been familiar with architecture amphibious, but it was not built on land but on the banks of river spaces, 2). In Kalimantan in particular and in Indonesia in general, naming amphibian houses in each region has different names and 3). The study of the development of the ark'a modulam foundation is still a preliminary study to formulate the basic form of amphibian foundations for simple dwellings that are expected to be industrialized. Therefore further research will be used in industrial product materials

Dr Hamza Abusnina

It is possible to, knowingly or unknowingly, damage underground gas services, water services, electrical services, etc. Incidents involving infrastructure damage are far more common than perceived; and these incidents result in hundreds of thousands, if not millions, of dollars in repair or replacement. Damages to underground facilities may occur by large construction contractors or by homeowners. The main objective of this research is two-fold: a) to determine the important risk factors contributing to the underground gas pipe damages; b) to identify inputs required for an effective evaluation and assessment of the risk encountered in exchange of information between different parties involved during the repair of underground gas pipelines. A predictive model will be developed based on machine learning algorithms (Logistic Regression) to be used in predicting the important risk factors affecting the underground Gas Pipe Damages. The research will systematically analyze the risk of underground gas pipeline network damage including; process the data collected from the agency, organizing/classifying the data based on certain parameters, processing the data, develop an integrated risk model and influence diagram. Next, Bayesian Network will be developed based on the derived important factors, and calculated probabilities for each attribute.

Bandar Abdullah AlMobark

Business Intelligence (BI) systems are key to deal with information in an organization and decision support. The study aims to examine BI adoption within Small and Medium-Sized Enterprises (SMEs) in Saudi Arabia. A survey targeted executive management from the SMEs selected for the research. The result of the study was "Improvements in data support" as the most BI benefit factors and "interfaces" as the most challenging factors on SMEs.

Rizka Reza Pahlevi, Aji Gautama Putrada

Aquaponics is a combined concept of aquaculture and hydroponics that offers a symbiotic relationship between the aquatic environment and the hydroponic environment and can be a solution to land crisis and food security problems. However, the use of conventional energy sources in supplying aquaponics systems is contradictory to the problem of the energy crisis. The aim of this study is to evaluate the adequacy of energy harvested from solar panels and wind turbines in meeting energy needs in aquaponics systems based on internet of things (IoT)-based measurements. The monitoring system built is reliable and has a centralized energy harvesting interface. Tests for energy harvesting and energy consumption were carried out for three days. Based on the test results, the total energy harvested from solar panels and wind turbines can cover 307% to 345% of energy in aquaponics systems. Solar energy gains supply 295%, and wind energy supplies 28%.

Wahyu Lelly Hana Setyanti, Sudarsih

Ecopreneurship is an environment based on entrepreneurial activities to fulfill their business goals that have an impact on ecotourism development. Marine ecotourism is one sector that has the potential to develop the ecopreneurship business concept. This paper focuses on how to take the potential of marine tourism based on community empowerment to encourage more entrepreneurs to overcome environmental problems. This study will examine the interface between entrepreneurs and the environment which is the domain of ecology. Business growth is expected to be sustainable in line with the maintenance of environmental quality. The analytical technique used is a descriptive analysis technique with a qualitative approach.

LJ Lantaya, Rene Bonifacio, Glenn Jabagat, Luigi John Ilongo, Eila Caryl Gwyn Lucday, Rafemay Maluenda

As the world advances to its course, some languages become indigenous and endangered at the same time due to the domination of significant languages; this implies understanding, preservation, and maintenance if we are looking forward to a healthy diversity of languages and coexistence. This study aims at analyzing how to conserve and sustain imperiled and indigenous dialects in the Philippines with limitations of the previous studies, identification of barriers, formulation of new perspectives, and possible solutions. The researchers used both quantitative and qualitative methods to analyze language preservation and maintenance in the Philippines. With that, the researchers employed secondary data from previous studies. The researchers have reflected those data to their current research to be analyzed along with the gathered data. These paved the way to analyzing the limitations of previous studies and barriers to the present analysis. The researchers utilized this concept to formulate an ideal perspective and possible solutions for the present study. This research concludes that endangerment among indigenous languages is imminent if not because of language preservation and maintenance, vital in achieving diversification and cultural awareness of different communities in the Philippines.

Syafwandi, Agus Suroso, Rizal Sugih Firmansyah

The rapid development of industry in Indonesia indirectly has an impact on the number of construction projects in the industrial area of Bekasi such as factory buildings, warehouses, offices, hotels, and hospitals. This research focuses on the influence of leadership and competence of project manager to project performance in industrial construction project. To find the effect of leadership and competence of project manager to project performance can be done with SEM PLS algorithm. The result show that leadership and competence of project manager has significant effect to project performance.

Pujiadi, Kartono, Y.L. Sukestiyarno, Mulyono

The anxiety experienced by students related to mathematics subjects is commonly referred to mathematics as anxiety subject. The purpose of this study was to determine the level of mathematics anxiety of high school students, thus providing an empirical analysis of high school students' math anxiety, especially in the province of Central Java. This research uses descriptive research method, with sampling using purposive sampling, namely from the population of high school students in Central Java Province, it is determined that students from all districts/ cities in Central Java as the research sample of 2,240 students. The data were collected using a mathematics anxiety measurement instrument from Freedman (mathpower.com) in the form of a questionnaire with 10 items, using a Likert scale model with 5 alternative answers. The score for filling out the questionnaire is classified into 4 categories of mathematics anxiety levels, namely high, medium, low, and no anxiety. The results showed: (1) The level of mathematics anxiety of high school students in Central Java was generally categorized as low anxiety, with an average score of mathematics anxiety of 26.89, (2) The mode of mathematics anxiety score of students was 24.00, also in the anxiety category. low, (3) the lowest average of students' math anxiety items was 1.82, and the highest average was 3.52.

Sutrimo, Kamid, Asrial, Bambang Hariyadi

The focus of this research is to identify the learning model that has the best possibility to teach ethnomathematics of the Muaro Jambi temple in geometry learning. The purpose of this study is to provide solutions for teaching mathematics that can improve creative thinking skills with the Muaro Jambi temple learning resources in geometry learning. This study uses a qualitative approach. The data findings were analyzed using descriptive analysis. Based on the research findings, it can be collected the Muaro Jambi temple which has the potential to be a source of geometry learning. The learning model that has the potential for teaching is a problem based learning model. Teachers should be able to apply ethnomathematical geometry learning with the Muaro Jambi temple with problem based learning. Theoretically, the ethnomathematics of the Muaro Jambi temple can be taught using problem based learning.

Dr. Muhammad Khan

COVID-19 has disturbed most of the businesses in the world. Education is the only industry that is completely moved to online mode in most countries around the world. e-Learning was the best way out for continuing education during the pandemic. This study aims to determine the challenges and barriers confronted during switching to online due to the COVID-19 pandemic. The contribution of this study is to evaluate the learners’ new capabilities in online education and to evaluate the feasibility of the virtual methods of learning.

Rene Marquez Bonifacio

Translanguaging is a complex process of combining two or more languages in a single utterance in reference to the complex linguistic and semiotic repertoires of languages employed. This study aims at probing how translanguaging supports Manobo’s social identity through the fluidity of linguistic boundaries. Using purposive sampling, I chose eight respondents based on specific criteria. To gather substantial data, I employed in-depth sociolinguistic interviews and ethnography, which were video-recorded to encapsulate the precision of the respondents’ narratives and real-life language use. The transcripts were analyzed to uncover the function of translanguaging in portraying the social identity of the respondents. The findings of the study reveal that Manobo people in Lumintao, Quezon, Bukidnon have embraced a multilingual identity because they employ translanguaging, a combination of Cebuano and Binukid languages, in interacting with others at school, market, workplace. Even though they speak Cebuano, their Manobo identity is apparent because of using Binukid lexis that was smoothly and automatically combined during conversations. Aside from that, their Manobo accent is evident which is an index of belonging to the Manobo cultural community.

Lea Baldoman, Justine Mae Beñales, Ellen Mae Cadeliña, Jona Lou Carmelotes, Mitchie Joy Dipay

Human language is subject to constant evolution driven by the need to reflect the world’s ongoing changes and becomes a more efficient means of communication. The term semantic change describes how words can have different meanings for different people, usually because the modern meaning differs from the original usage. The primary purpose of this study is to analyze related research journal articles about the semantics change of the Binukid language in reflection of modernity in the Province of Bukidnon, Mindanao, Philippines. This study reviews the growing scholarly literature that takes up the term semantic change and discusses the rise of epistemic meaning of words. Moreover, the researchers focus on the developments and challenges of semantic change in communication over time. After reviewing reputable journals, the researchers consider how semantic changes’ underlying theories and evolution affect today’s generation’s communication. Hence, semantic change categorizations’ relationship to the nature of semantic change remains obscure despite the efforts of the researchers in this field.

Jerrymie Mila, Jemeah Ann Mariscal, Karl Ferdie Mae Lofranco, Filyn Grace Macanim

Multilingualism poses several issues around the world, and language preservation is a helpful tool to preserve endangered languages. This study aims at analyzing how multilingualism helps in the preservation of the Kamayo language in Surigao del Sur, Philippines despite language urbanization. The data were gathered generally through reviewing available literature and studies related to the study. The study finds out that multilingualism and language preservation interrelates as multilingualism plays a role in language preservation but with limitation as existing languages such as the Kamayo language, are still not prioritize to be used as the medium in the institutions in the community. The existence of multilingualism and its practices such as MTB-MLE in the educational setting helps provide opportunities for languages to be used, but a need for policy revision to give every language its rights to be used and enriched by its speakers for language development for the future generations.

Erim, Costly Manyo

Education is an indispensable tool for the improvement of life of people especially women. Educating a woman is crucial to her self-improvement and liberation from all forms’ limitations. An educated woman can adopt the best family method to control the size of her family, enhance her children's health and reduce infant mortality rate. When women are educationally empowered, they are well able to face challenging situations, fight against traditional roles that are repugnant to rural justice and live happier and fulfilled lives: The study investigated whether the activities of faith-based Christians organizations influence the educational empowerment of female members in the Southern Senatorial District of Cross River State, Nigeria. The population was (8,800) registered female members domiciled in one hundred and fifty-nine (159) churches in the study area. Ten percent (10%) of the population which was 880 respondents constituted the sample, this was done using purposive and simple random sampling techniques. The data was analyzed using one way analysis of variance (ANOVA). The result revealed that the activities of faith-based Christian organizations in provision of educational facilities significantly influence the empowerment of female members in all the six dimension of empowerment which include: skills acquisition, income generation, decision-making, reducing illiteracy rate, increased food productivity and healthy life style. Based on the findings of the study, it was recommended that faith-based Christian organization should partner with charity or donor agencies to attract finds to sponsor more educational programmes that are meant to enable women acquire skills, knowledge an attitude to be useful to themselves and the society.