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IJSTR >> Volume 4 - Issue 12, December 2015 Edition

International Journal of Scientific & Technology Research  
International Journal of Scientific & Technology Research

Website: http://www.ijstr.org

ISSN 2277-8616

Screening Of Marine Bacteria For Pharmacological Activities

[Full Text]



S. Vijayalakshmi



Keywords: Analgesic activity, Animal model, Anti inflammatory, CNS depressant activity, Ethyl acetate extracts,Marine bacteria and Pharmacological drug.



Abstract: The symbiotic and associated four marine bacteria BR1 (Flavobacterium sp.) isolated from Barnacle Balanus amphitrite,EM13 (Micrococus sp.) from Seaweed Enteromorpha compressa,PC4 (Alcaligenes sp.) from Ascidian Polyclinum constellatum and SW12 (Bacillus sp.) from seawater were cultured and extracted for pharmacological activities. The ethyl acetate extracts of these marine bacterial culture supernatants were screened for pharmacological activities such as Anti inflammatory, Analgesic and CNS depressant activities using experimental animal model. In this study,SW12 exhibited high activity for both Anti inflammatory and Analgesic. Especially which exhibited highest analgesic activity than standard drug pethidine. Another one PC4 showed highest analgesic activity similar to standard drug. Other two extracts EM13 and BR1 showed high activity in CNS depressant. Based on the result, SW12 is a highly potent strain, it may produce novel compound for pharmacological drug.



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