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IJSTR >> Volume 10 - Issue 10, October 2021 Edition



International Journal of Scientific & Technology Research  
International Journal of Scientific & Technology Research

Website: http://www.ijstr.org

ISSN 2277-8616



Antimicrobial Activity And Phytochemical Screening Of Split Gill Mushroom (Schizophyllum Commune) Ethanolic Extract

[Full Text]

 

AUTHOR(S)

Ricky B. Acanto, Van Helen S. Cuaderes

 

KEYWORDS

antimicrobial activity, ethanolic extract, macrofungi, phytochemical screening, Schizophyllum commune

 

ABSTRACT

Split gill mushroom (Schizophyllum commune) is one of the most widespread fungal species with various uses among communities, especially in the countryside. With its favorable characteristics, this macrofungi shows potential to be utilized in the field of natural products. The study aims to ascertain the antimicrobial effects and determine the active components present in the ethanolic extracts. The extract’s antibacterial activity was determined using Kirby-Bauer Disk Diffusion Assay, antifungal susceptibility through Poisoned Food Method, and minimum inhibitory concentration (MIC) through Microtiter Well Assay. Qualitative phytochemical analysis was carried out using the test tube method. Results revealed that gram-negative bacteria were resistant to the different concentrations of the extracts; however, gram-positive test bacteria were susceptible to any extract concentration. Additionally, MICs showed that a lower concentration of the extract was required to inhibit the growth of gram-positive than the gram-negative bacteria. The increasing concentration of extracts showed more significant fungal growth inhibition. Saponins, tannins, alkaloids, flavonoids, terpenoids, proteins, and carbohydrates were identified through the phytochemical screening. Ethanolic extracts of S. commune showed effectiveness against the growth of gram-positive bacteria and fungi due to different active components present. Further studies may be conducted to explore the potential of this macrofungi.

 

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