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IJSTR >> Volume 2- Issue 5, May 2013 Edition

International Journal of Scientific & Technology Research  
International Journal of Scientific & Technology Research

Website: http://www.ijstr.org

ISSN 2277-8616

Phytochemical Analysis, Cytotoxic And Antioxidant Potential Of Ipomoea Pes Caprae(L)R.Br And Merremia Umbellata(L.)H. Hallier.

[Full Text]



Minakshi Ganjir, Dipti Ranjan Behera, Sunita Bhatnagar



Keywords: Ipomoea pes-caprae, Merremia umbellata, cytotoxic, antioxidant, spectral analysis, DPPH assay, FRAP assay



Abstract: Ipomoea pes-caprae and Merremia umbellata initially belonged to the same genus Ipomoea, later both were separated into different genus on the basis of morphological differences. In this study both the medicinal plants were compared using phytochemical analysis, cytotoxic activity and antioxidant potential. Phytochemical tests revealed lots of similarities than variation. The only difference in case of phytochemical analysis of the two plants was in the detection of tannins which was present in all the samples of Ipomoea pes-caprae while it was present only in polar extract in Merremia umbellata. In spectral analysis most of the extracts showed similar profile, except for hexane extracts. Majority of peaks were similar with a minor peak here or there. Regarding cytotoxic activity Ipomoea pes caprae showed better results(more than 80%) as compared to Merremia umbellata which showed less than 75% cytotoxic activity. Ipomoea pes capre revealed marginally better antioxidant properties in comparision to Merremia umbellata.



Pongprayoon, U, Baeckström, P, Jacobsson, U, Lindström, M, Bohlin, L (1992). Antispasmodic activity of beta-damascenone and E-phytol isolated from Ipomoea pes-caprae. Planta Medica, 58, 464-466.

[2]. Sangameswaran, B, Singh, R, Balakrishnan, BR. Jayakan, B.(2008) Anti-hyperglycemic and anti-hyperlipidemic effect of Ipomoea reniformis chois an alloxan induced diabetic rats. Journal of Research and education in India medicine.13 : 27-30.

[3]. Umamaheshwari .G, Ramanathan, T, Shanmugapriya, R. (2012). Antioxidant and Radical Scavenging effect of Ipomoea pes-caprae Linn. R.Br. International Journal of PharmTech Research. 3, 1177-1180.

[4]. Yan, J, Bi, HH, Liu, YZ, Zhang, M, Zhou, ZY, Tan, JW.(2010). Phenolic compounds from Merremia umbellata subsp. orientalis and their allelopathic effects on Arabidopsis seed germination.Molecules,15, 8241-8250.

[5]. Rai, PK, Lal, RH.(2010). Ethno medicinal plant resources of Mizoram, India: Implication of Traditional knowledge in health care system. Ethnobotanical leaflets,14, 274-305.

[6]. Harborne JB. (1984) Phytochemical methods: A guide to modern techniques of plant analysis. ). Harborne JB (Ed). Chapman and Hall, London, UK.

[7]. Bhatnagar, S, Pattanaik, SR(2012). Comparative analysis of cytotoxic and antioxidant activities of leaf and bark extracts of clerodenrum viscosum and Clerodendrum phlomidis. International Journal of Biomedical and Advance Research, 3, 385-390.

[8]. Masoko, P , Eloff, JN.(2007) Screening of 24 south african combretum and six terminalia Species (Combretaceae). Afr J trad Com Alt Med. 4, 231-239.

[9]. Deby, C, and Margotteaux G. (1970). Relationship between essential fatty acids and tissue antioxidant levels in mice. C R Seances Soc Biol Fil, 165, 2675-2681.

[10]. Ahmad S and Beigh, SH,(2009) Ascorbic acid,Carotenoids, Total Phenolic content and antioxidant activity of various genotypes of Brassica Oleracea encephala. J. Med Biol Sci, , 3, 1-8.

[11]. Suresh KCA, Thamizhmozhi,M, Saravanan,C, Gude Suresh, KG, Sasi,K (2012) Evaluation of anti-inflammatory activity of Ipomoea staphylina In carrageenan-induced paw edema in rats. Int J Pharm Sci Rev Res, 16, 67-69.

[12]. Parekh, KK, Patel AM, Modi, AJ, Chandrashekhar,HR, (2012). Antioxidant and Cytotoxic Activities of Few Selected Ipomoea Species. Pharmacologia, 3: 377-386

[13]. Morimoto, T, Nagatsu, A, Muratami, N, El-Baroty, GSMY, Moussa, MA, Shallan, Sakakibara, J. (2007). Anti-tumor-promoting Contribution to the aroma, biological activities,glyceroglycolipids from the green alga, Clorella minerals, protein, pigments and lipid contents of thevulgaris. Phytochemistry, 5: 1433-1437

[14]. Masuda T, Yonemori S, Oyama Y, Takeda Y, Tanaka T, Andoh T, Shinohara A, Nakata M (1999) Evaluation of the antioxidant activity of environmental plants: activity of the leaf extracts from seashore plants. Journal of Agriculture and Food Chemistry 1999, 47, 1749-1754.